SOME DRUGS CONTRAINDICATED IN PREGNANCY
This chart represents information on select drugs
that are contraindicated (Pregnancy category X) for
women who are pregnant. This is not an inclusive
list of products that carry that pregnancy category.
Those drugs that are contraindicated at a certain
phase of the pregnancy are listed next to the product
name. For more information on specific drug
monographs, see product entries or consult the
manufacturer.
ALLERGIC DISORDERS
Vistaril (hydroxyzine) Early pregnancy
CARDIOVASCULAR SYSTEM
Advicor (niacin ext-rel/lovastatin)
Aggrenox (dipyridamole/aspirin) 3rd trimester
Altoprev (lovastatin)
Bayer (aspirin) 3rd trimester
Caduet (amlodipine/atorvastatin)
Coumadin (warfarin sodium)
Crestor (rosuvastatin)
Ecotrin (aspirin) 3rd trimester
Lescol (fluvastatin)
Lescol XL (fluvastatin)
Letairis (ambrisentan)
Lipitor (atorvastatin)
Livalo (pitavastatin)
Lovastatin tabs
Multaq (dronedarone)
Pravachol (pravastatin)
Simcor (niacin ext-rel/simvastatin)
Tracleer (bosentan)
Vytorin (ezetimibe/simvastatin)
Zocor (simvastatin)
CENTRAL NERVOUS SYSTEM
Beyaz (drospirenone/ethinyl estradiol)
Doral (quazepam)
Estazolam
Flurazepam
Halcion (triazolam)
Restoril (temazepam)
Vistaril (hydroxyzine) Early pregnancy
Yaz (drospirenone/ethinyl estradiol)
DERMATOLOGICAL DISORDERS
Amnesteem (isotretinoin)
Avage (tazarotene)
Beyaz (drospirenone/ethinyl estradiol)
Carac (fluorouracil)
Claravis (isotretinoin)
Efudex (fluorouracil)
Estrostep Fe (norethindrone acetate/ethinyl estradiol)
Fluoroplex (fluorouracil)
Loryna (drospirenone/ethinyl estradiol)
Ortho Tri-Cyclen 28 (norgestimate/ethinyl estradiol)
Propecia (finasteride)
Silvadene (silver sulfadiazine) Late pregnancy
Solaraze (diclofenac sodium) 3rd trimester
Soriatane (acitretin)
Sotret (isotretinoin)
SSD (silver sulfadiazine) Late pregnancy
SSD AF (silver sulfadiazine) Late pregnancy
Tazorac (tazarotene)
Tilia Fe (norethindrone acetate/ethinyl estradiol)
Tri-Legest Fe (norethindrone acetate/ethinyl estradiol)
Tri-previfem (norgestimate/ethinyl estradiol)
Tri-sprintec (norgestimate/ethinyl estradiol)
Yaz (drospirenone/ethinyl estradiol)
ENDOCRINE DISORDERS
Androderm (testosterone)
Androgel (testosterone)
Android (methyltestosterone)
Axiron (testosterone)
Delatestryl (testosterone enanthate)
Depo-testosterone (testosterone cypionate)
Egrifta (tesamorelin)
Fluoxymesterone
Fortesta (testosterone)
Lupron (leuprolide acetate)
Methitest (methyltestosterone)
Oxandrin (oxandrolone)
Striant (testosterone)
Supprelin LA (histrelin acetate)
Synarel (nafarelin)
Testim (testosterone)
Testred (methyltestosterone)
GASTROINTESTINAL TRACT
Cytotec (misoprostol)
INFECTIONS & INFESTATIONS
Bactrim (sulfamethoxazole/trimethoprim) 3rd trimester
Copegus (ribavirin)
Flagyl (metronidazole) 1st trimester for trichomoniasis
Furadantin (nitrofurantoin) Pregnancy at term
Gantrisin (sulfisoxazole) 3rd trimester
Grifulvin V (griseofulvin)
Gris-Peg (griseofulvin)
Macrobid (nitrofurantoin as macrocrystals and monohydrate)
Pregnancy at term
Macrodantin (nitrofurantoin macrocrystals) Pregnancy at term
Rebetol (ribavirin)
Rebetron (ribavirin/interferon alfa -2b)
Septra (sulfamethoxazole/trimethoprim) 3rd trimester
Sulfadiazine Pregnancy at term
Tindamax (tinidazole) 1st trimester
Urobiotic-250 (oxytetracycline HCl/sulfamethizole/ phenazopyridine) Late pregnancy
Virazole (ribavirin)
METABOLIC DISORDERS
Zavesca (miglustat)
MUSCULOSKELETAL DISORDERS
Advil (ibuprofen) 3rd trimester
Aleve (naproxen sodium) 3rd trimester
Ansaid (flurbiprofen) Late pregnancy
Arava (leflunomide)
Arthrotec (diclofenac sodium/misoprostol)
Bayer (aspirin) 3rd trimester
BC Arthritis Strength (aspirin/caffeine/salicylamide) 3rd trimester
Carisoprodol/aspirin/codeine 3rd trimester
Cataflam (diclofenac potassium) Late pregnancy
Celebrex (celecoxib) 3rd trimester
Choline magnesium trisalicylate Pregnancy at term
Dantrium (dantrolene)
Daypro (oxaprozin) 3rd trimester
Diclofenac sodium Late pregnancy
Diflunisal 3rd trimester
Duexis (ibuprofen/famotidine) Late pregnancy (≥30wks)
Ecotrin (aspirin) 3rd trimester
Etodolac Late pregnancy
Evista (raloxifene HCl)
Feldene (piroxicam) Late pregnancy
Ibuprofen 3rd trimester
Ketoprofen Late pregnancy
Mobic (meloxicam) 3rd trimester
Nabumetone 3rd trimester
Nalfon (fenoprofen calcium) 3rd trimester
Naprelan (naproxen) 3rd trimester
Probenecid + Colchicine
Prolia (denosumab)
Rheumatrex (methotrexate sodium)
Salsalate 3rd trimester
Vimovo (naproxen/esomeprazole) Late pregnancy (≥30wks)
Zipsor (diclofenac potassium) Late pregnancy
NEOPLASMS
Bexxar (tositumomab)
Casodex (bicalutamide)
Delestrogen (estradiol valerate)
Efudex (fluorouracil)
Eligard (leuprolide acetate)
Estrace (estradiol)
Evista (raloxifene HCl)
Firmagon (degarelix)
Fluoxymesterone
Menest (esterified estrogens)
Revlimid (lenalidomide)
Targretin (bexarotene)
Thalomid (thalidomide)
Trelstar (triptorelan pamoate)
Trexall (methotrexate)
Vantas (histrelin acetate)
Zytiga (abiraterone acetate)
NUTRITION
Didrex (benzphetamine)
Fosteum (genistein/citrated zinc/cholecalciferol)
Megace ES (megestrol acetate)
Megace Suspension (megestrol acetate)
Xenical (orlistat)
OB/GYN
ALL ORAL CONTRACEPTIVES
ALL HORMONE REPLACEMENT THERAPY
Advil (ibuprofen) 3rd trimester
Aleve (naproxen sodium) 3rd trimester
Aygestin (norethindrone acetate)
Betadine douche (povidone-iodine)
Bravelle (urofollitropin)
Cataflam (diclofenac potassium) Late pregnancy
Celebrex (celecoxib) 3rd trimester
Cetrotide (cetrorelix)
Clomid (clomiphene citrate)
Depo-subQ provera (medroxyprogesterone acetate)
Endometrin (micronized progesterone) Ectopic pregnancy
Flagyl (metronidazole) 1st trimester for trichomoniasis
Follistim (follitropin beta)
Ganirelix acetate
Gonal-F (follitropin alfa)
Ibuprofen 3rd trimester
Lupron Depot (leuprolide acetate)
Menopur (menoptropins)
Methergine (methylergonovine)
Midol teen (acetaminophen/pamabrom) 3rd trimester
Mifeprex (mifepristone)
Naprelan (naproxen) 3rd trimester
Ovidrel (choriogonadotropin alfa)
Ponstel (mefenamic acid) Late pregnancy
Repronex 75 IU (follicle-stimulating hormone/luteinizing hormone)
Serophene (clomiphene citrate)
Synarel (nafarelin acetate)
Tindamax (tinidazole) 1st trimester
Zoladex (goserelin)
PAIN MANAGEMENT
Advil (ibuprofen) 3rd trimester
Advil Migraine (ibuprofen) 3rd trimester
Aleve (naproxen sodium) 3rd trimester
Bayer (aspirin) 3rd trimester
BC Original Formula (aspirin/caffeine/salicylamide) 3rd trimester
Caldolor (ibuprofen) 3rd trimester
Cataflam (diclofenac potassium) Late pregnancy
Celebrex (celecoxib) 3rd trimester
Choline magnesium trisalicylate Pregnancy at term
D.H.E. 45 (dihydroergotamine mesylate)
Diflunisal 3rd trimester
Ergotamine tartrate/caffeine
Etodolac Late pregnancy
Excedrin Migraine (acetaminophen/aspirin/ caffeine) 3rd trimester
Fiorinal (butalbital/aspirin/caffeine) 3rd trimester
Fiorinal w. Codeine (butalbital/aspirin/caffeine/ codeine phosphate) 3rd trimester
Ibudone (hydrocodone bitartrate/ibuprofen) 3rd trimester
Ketorolac Late pregnancy
Migranal (dihydroergotamine mesylate)
Motrin Migraine Pain (ibuprofen) 3rd trimester
Nalfon (fenoprofen calcium) 3rd trimester
Naprelan (naproxen) 3rd trimester
Percodan (oxycodone HCl/aspirin) 3rd trimester
Ponstel (mefenamic acid) Late pregnancy
Synalgos-DC (dihydrocodeine bitartrate/aspirin/caffeine) 3rd trimester
Vicoprofen (hydrocodone bitartrate/ibuprofen) 3rd trimester
RESPIRATORY TRACT
None available
UROGENITAL SYSTEM
Avodart (dutasteride HCl) AVOID HANDLING CAPSULES
Caverject (alprostadil)
Edex (alprostadil)
Jalyn (dutasteride/tamsulosin HCl)
Lithostat (acetohydroxamic acid)
Proscar (finasteride) AVOID HANDLING CRUSHED/BROKEN TABLETS
*Not an inclusive list.
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