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Drug Interactions Diabetics Should Avoid

Patients with diabetes have a higher pill burden than the general population, so pharmacists should pay particular attention to potential drug interactions with antidiabetic agents. Drug interactions may decrease medication efficacy or increase toxicity, and greater pill burden challenges adherence and adds to adverse effects. Past research has shown that the benefits of carefully selected cardiovascular medications outweigh their risks. In addition, pharmacists should know the following facts: ·         Sulfonylureas, thiazolidinediones, meglitinides, and dipeptidyl-peptidase-4 inhibitors (DDP-4s) are most susceptible to interactions. ·         Glucagon-like peptide-1 (GLP-1) agonists and sodium-glucose transport protein (SGLT-2) inhibitors are least affected by drug interactions. ·         Clinicians should consider altered absorption and transpor...

FDA Alert – Oral Nizoral (ketoconazole): Unapproved Use Continues, Linked to Patient Death

Information sourced from FDA: Nizoral (ketoconazole) Oral Tablets: Drug Safety Communication - Prescribing for Unapproved Uses including Skin and Nail Infections Continues; Linked to Patient Death ISSUE: FDA is warning health care professionals to avoid prescribing the antifungal medicine ketoconazole oral tablets to treat skin and nail fungal infections. Use of this medication carries the risk of serious liver damage, adrenal gland problems, and harmful interactions with other medicines that outweigh its benefit in treating these conditions, which are not approved uses of the drug. FDA approved label changes for oral ketoconazole tablets in 2013 to reflect these serious risks and to remove the indications for treatment of skin and nail fungal infections. However, an FDA safety review found that oral ketoconazole continues to be prescribed for these types of conditions. Since the 2013 labeling change, one patient death has been reported to the FDA due to liver failure associated wit...

SAY GOODBYE TO COUGH PHLEGM FLU CLEAN THE LUNGS FOREVER WITH THIS OLD REMEDY

The recipe presented in this article is extremely treating excessive mucus ad coughing. It is all-natural and safe to use for both children and adults.  Carrots are very beneficial for diabetics and people with high blood pressure. It is recommended to opt for a fresh carrot juice, as it has higher concentration of nutrients when compared to raw carrots.  What Makes Carrots Good for You? Boost immunity Promote cardiovascular health Lower cholesterol Prevent cancer Skin-friendly and reduce acne Promote detoxification Contain calcium which improves digestion Excellent source of nutrients which are good for the skin RECIPE Ingredients : ½ kg of carrots Some water 3-4 tbsp. of organic honey Instructions: Peel the carrots and boil them until soft. Keep the liquid in which they have been boiled Mix the liquid with the carrots Add 3-4 tbsp. of organic honey in the water and add the carrot puree Store in cool place Use: Take 3-4 tablespoons of the syrup and y...

Death Risk With Off-Label Oral Ketoconazole Use, FDA Warns

The US Food and Drug Administration (FDA) is warning clinicians against the off-label prescribing of ketoconazole tablets (Nizoral, Janssen Pharmaceuticals) to treat skin and nail fungal infections because the risk for serious liver damage and death outweighs the benefits. In July 2013, the FDA removed skin and nail fungal infections as indications for ketoconazole tablets in light of possible adverse events, which also include adrenal gland problems and harmful interactions with other drugs. The agency revised the label to warn that patients with no obvious risk factors for liver disease had developed serious hepatotoxicity after taking the drug, leading to liver transplants or death in some cases. However, clinicians have continued to prescribe ketoconazole tablets for skin and nail fungal infections despite the label change, according to an FDA safety review. Such infections were the only diagnoses cited for the tablets during 2014 and the first 6 months of 2015, according to a da...

FDA: Avoid Cipro, Similar Drugs for Common Infections — Agency says risks outweigh benefits

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05.12.2016 INFECTIOUS DISEASE WASHINGTON Fluoroquinolone antibiotics, the class that includes ciprofloxacin (Cipro), ciprofloxacin, getifloxacin, ofloxacin, pefloxacin, sparfloxacin, levofloxacin , e.t.c should not be used to treat uncomplicated infections such as sinusitis, bronchitis, and urinary tract infections for which other drug types are effective, the FDA announced Thursday. Only patients with these conditions who can't be treated with other agents should receive fluoroquinolones, the agency said. "An FDA safety review has shown that fluoroquinolones when used systemically (i.e., tablets, capsules, and injectable) are associated with disabling and potentially permanent serious side effects that can occur together. These side effects can involve the tendons, muscles, joints, nerves, and central nervous system," the FDA said. Labels and medication guides for these agents will be updated to reflect the review's findings . The FDA noted that it has had ...

This is What Your Period is Saying About Your Health

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Women have to struggle with this every month. The period make them feeling sick, bloated and sometimes the pain that this cause is real nightmare. But we can’t do anything about this because this is a natural and normal body function. All women shall know this fact, because it may discover serious health issue. But women aren’t so exited to talk about their period and usually those problems can be unnoticed. If you know this facts, you will be able to identify the signs, to be more informed to help yourself in time if there is a health issue. Color and flow, the period can be categorized in three type of colors: Mashed frozen blueberries Strawberry jam Cranberry juice According to Dr. Alisa Vitti, a holistic health counselor and functional nutritionist. The texture which seems to frozen blueberries shows high estrogen levels, making the cycle heavier than it should be, because the uterus is thicker than it shall be. The color like strawberry jam is showing low l...

Boil Bananas Before Bed, Drink the Liquid and You Won’t Believe What Happens to Your Sleep

We’ve all had those restless nights of tossing and turning, staring at the ceiling, unable to get more than a couple hours of shuteye. The more you worry about not sleeping, the more your mind races, and next thing you know, the sun is peeking through the window. I’ve spent one too many nights this way and needed to put an end to my poor sleeping patterns. I came across this delicious tea recipe and it improved my cycle completely. Irregular sleeping patterns or even insomnia can stem from several different things like depression, stress and anxiety. Almost every night, I would get into bed and my mind would be racing. Whether I was thinking about work, family, or simply the things I needed to get done the next day, I just couldn’t allow myself to relax. If your mind is active, chances are you won’t fall asleep. Certain medications can also cause insomnia. Pain medications, antihistamines, and heart and blood pressure medicines are among the many that contribu...